Breathe easier, naturally. Clinically studied probiotic strains that reduce the frequency and severity of allergic rhinitis and asthma episodes.
☆☆☆☆☆No reviews yet422-child double-blind RCT — 8 weeks of BIFIASTHM supplementation significantly reduced asthmatic episode frequency and severity; ALLERFLORA reduced nasal symptom scores and ARIA classification in allergic rhinitis.
Lorbiotics-Cold is a clinically targeted 5-strain synbiotic designed to correct the Th2-dominant immune imbalance that drives allergic asthma and allergic rhinitis. It combines L. salivarius, B. breve, L. plantarum, L. paracasei (ST11), and B. subtilis with Vitamins C, D3, and a prebiotic substrate.
Instead of masking symptoms, it addresses the root cause — restoring Th1/Th2 balance. In allergic conditions, Th2 bias triggers excess IL-4, IL-5, and IL-13, leading to IgE overproduction, mast cell activation, and eosinophil-driven inflammation.
“A clinically targeted 5-strain synbiotic designed to correct the Th2-dominant immune imbalance that drives allergic asthma and allergic rhinitis.”
Lorbiotics Cold · Immunology
The documented biological pathway — exactly how each component acts inside the body.
L. salivarius and L. plantarum activate mucosal dendritic cells through TLR-2/6 signalling, driving IL-12 and IFN-γ production that counters Th2 dominance. This Th1 shift favours IgG4 over IgE class switching, reducing allergen-specific IgE and limiting mast cell sensitisation in respiratory tissues.
B. breve promotes allergen-specific Tregs via TGF-β and IL-10, establishing active immune tolerance. Vitamin D3 enhances the effect by supporting tolerogenic dendritic cells and boosting Treg-derived IL-10 in bronchial and nasal mucosa.
The exact composition of Lorbiotics Cold — each organism and active listed at its formulated dose.
| Organism / active | Documented role | Dose |
|---|---|---|
| Lactobacillus salivarius | — | 5 B CFU |
| Bifidobacterium breve | — | 5 B CFU |
| Lactobacillus plantarum | — | 5 B CFU |
| Lactobacillus paracasei | — | 5 B CFU |
| Bacillus subtilis | — | 5 B CFU |
| Vitamin C | — | 80 mg |
| Vitamin D3 | — | 1000 IU |
| Prebiotic as standardized | — | — |
1–2 sachets/capsules daily, ideally beginning 8 weeks before allergy season. For year-round allergic rhinitis or asthma: 1 sachet/capsule daily as maintenance. Or as advised by physician.
Capsule / Sachet · 60 per Pack
With Vitamin C 80 mg, Vitamin D3 1000 IU & prebiotic. Begin 8 weeks before allergy season for best results.
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Every claim on this page traces back to published literature. The full citation list for Lorbiotics Cold.
