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Lorbiotics · LPB-HE-001
Clinical DomainHepatology

Lorbiotics NAFLD

Comprehensive liver protection when fatty liver threatens your health. Addresses the root cause — gut-derived inflammation that drives fatty liver progression.

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12BCFU at expiry · per dose
6Active strains
Capsule / SachetDosage form
  • Capsules
  • Allergen Free
  • In Vitro Test
  • Clinical Test
  • 24 Month Stability
1
16W
The headline result

16-week minimum course recommended for NAFLD/NASH with liver enzyme monitoring — C. butyricum butyrate provides dual gut barrier repair and hepatic HDAC inhibition for profibrotic pathway suppression.

The science

Why NAFLD works.

NAFLD is a hepatology-focused synbiotic designed as an adjunct for managing Non-Alcoholic Fatty Liver Disease (NAFLD), NASH, and associated gut conditions including Crohn’s disease, ulcerative colitis, and C. difficile-associated diarrhoea.

It combines four clinically selected probiotic strains — Streptococcus faecalis, Clostridium butyricum, Bacillus mesentericus, and Bacillus coagulans — with Vitamin C and a postbiotic fraction to precisely target the gut-liver axis.

Therapeutic targets
  • 01
    NAFLD/NASH management
  • 02
    Hepatic enzyme normalisation
  • 03
    Hepatic fibrosis prevention
  • 04
    IBD support
  • 05
    C. difficile-associated diarrhoea
  • 06
    Hepatic antioxidant protection
  • 07
    Dual gut barrier + liver support
  • 08
    Immediate & long-term action
  • 09
    Comprehensive metabolic wellness

NAFLD is a hepatology-focused synbiotic designed as an adjunct for managing Non-Alcoholic Fatty Liver Disease (NAFLD), NASH, and associated gut conditions including Crohn’s disease, ulcerative colitis, and C.

Lorbiotics NAFLD · Hepatology
Mechanism of action

How it works, step by step.

The documented biological pathway — exactly how each component acts inside the body.

01

In NAFLD, gut dysbiosis increases intestinal permeability (“leaky gut”), allowing excess LPS, microbial metabolites, and secondary bile acids to enter the portal vein. This triggers hepatic inflammation via TLR-4 activation on Kupffer cells, promoting progression from simple steatosis to NASH and fibrosis.

02

NAFLD interrupts this process at multiple levels:

03

Clostridium butyricum — the gut’s premier butyrate producer — strengthens the intestinal barrier (reducing LPS translocation) and acts as a potent HDAC inhibitor in the liver, suppressing profibrotic pathways in hepatic stellate cells.

04

The Bacillus species provide spore stability and broad-spectrum antimicrobials that help restore a healthier, butyrate-rich microbiome.

05

Together, the multi-strain blend delivers synergistic, multi-point modulation of the gut-liver axis that single-strain probiotics cannot achieve.

06

Bacillus mesentericus: Proteolytic & lipolytic enzymes to control putrefactive bacteria

07

Bacillus coagulans: Lactic acid + bacteriocins for colonization resistance

08

Postbiotic fraction: Rapid anti-inflammatory PRR activation to calm Kupffer cells

09

Vitamin C: Supports hepatic detoxification and antioxidant protection

10

Perfect for premium liver and gut-liver axis formulations.

Inside the formula

Every ingredient earns its place.

The exact composition of Lorbiotics NAFLD — each organism and active listed at its formulated dose.

Composition · Lorbiotics NAFLDLPB-HE-001
Organism / activeDocumented roleDose
Streptococcus fecalis2 B CFU
Clostridium butyricum3 B CFU
Bacillus mesentericus3 B CFU
Bacillus coagulans3 B CFU
Postbiotic fraction as standardized
Vitamin CAscorbic acid80 mg
The practical bits

How to take it.

Dosage

1–2 sachets/capsules daily, with meals. For NAFLD/NASH: minimum 16-week course with liver enzyme monitoring. Or as advised by hepatologist / physician.

In the pack

Capsule / Sachet · 60 per Pack

With postbiotic fraction and Vitamin C 80 mg for hepatic antioxidant and immune support.

Certifications

  • WHO-GMP
  • ISO 13485
  • Allergen Free
  • Clinical Test
  • 24 Month Stability
Note: Not for medicinal use or for curative action. Recommended to use as food supplement only
Reviews

What people say after they've actually taken it.

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Evidence base

Peer-reviewed references.

Every claim on this page traces back to published literature. The full citation list for Lorbiotics NAFLD.

  1. 01Endo H, et al. Nutrients. 2019 11(9):2110.
  2. 02Probiotical S.p.A. LPB-HE-NAFLD · S. faecalis + C. butyricum + B. mesentericus + B. coagulans 8B + Postbiotic + Vit C · 60 Caps
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What people stack with this formula.